Asia-ARVO 2015

Feb 16 - 19, 2015 Yokohama, Japan

Program

  2015 Asia-ARVO Program at a glance
*As of Nov. 17, 2014

2015 Asia-ARVO Itinerary Planner  

View your submitted abstract proof by accessing the Itinerary Planner

The Itinerary Planner provides you with:

  • Overall program summary schedule
  • Details of Paper, Poster, and Invited Speaker sessions
  • Abstracts for Free Paper and Poster Presentations
  • An optional Itinerary Planner tool for you to create and print off a personalized schedule

 



Plenary lectures

 
 
Yamanaka   Recent progress in iPS cell research and application
Thursday, Feb 19; 4:10 – 5:10pm
Room 1 - Main Hall

Chairperson: Kazuo Tsubota
Keio University School of Medicine, Japan
Speaker: Shinya Yamanaka, MD, PhD
Center for iPS Cell Research and Application, Kyoto University

Induced pluripotent stem cells (iPSCs) were originally generated from mouse and human skin fibroblasts by introducing four identified transcription factor genes. As iPSCs have the ability to proliferate almost indefinitely and differentiate into multiple lineages, there are great hopes for medical and pharmaceutical applications. Many improvements have been achieved in iPSC production in both safety and efficacy.
iPSCs can be generated from various genetically identified individuals including patients. These iPSCs and subsequently differentiated target cells/ tissues would provide unprecedented opportunities in regenerative medicine, disease modelling, proof-of-concept studies in drug development, drug screening, and future personalized medicine.


 

Takahashi Application of iPS cells to retinal disease
Tuesday, Feb 17; 11:10am – 12:10pm
Room 1 - Main Hall

Chairperson: Tatsuro Ishibashi
Graduate School of Medical Sciences, Kyushu University, Japan
Speaker: Masayo Takahashi, MD, PhD, FARVO
Laboratory for Retinal Regeneration, RIKEN Center for Developmental Biology 

We have started clinical research using iPS cells for Age-related macular degeneration (AMD). Now we are preparing the first patinet’s iPSC-derived RPE (hiPSC-RPE) cell sheets optimized to meet clinical requirements including quality, quantity, consistency, and safety. We also evaluate the photoreceptor transplantation using iPS-derived 3D retinal induction methods. We observed survival of photoreceptor cells with outer segments for more than 6 months.
Thus, iPS cell-derived retinal cell transplantation is promising. However, the effect of the treatments will be limited for the first decade. We should know precisely about the possibility and the limitation of the therapy.


 

Yoshimura Gene polymorphism-based personalized patient care in AMD
Thursday, Feb 19; 11:10am – 12:10pm
Room 1 - Main Hall

Chairperson: Yozo Miyake
Aichi Medical University, Japan
Speaker: Nagahisa Yoshimura, MD, PhD, FARVO
Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medical Science 

Discovery of CFH and ARMS2 as susceptibility genes of age-related macular degeneration (AMD) established the importance of genetic polymorphisms in the development of AMD and now more than 10 genes are known to be associated with AMD. On the other hand, only few studies are available to show a positive contribution of gene polymorphisms to clinical phenotypes of AMD. Most of the studies showing such negative contribution focus on disease-susceptibility genes and rather limited information on phenotypes is used. However, our recent genome-wide association study revealed that ARMS2 is a strong predictor of AMD prognosis. Furthermore, we found that MMP20 is associated with the lesion size but not with the onset of AMD, which suggests MMP20 would be a novel target for the treatment of AMD. So, gene polymorphisms are important not only for the development of AMD but also play an important role in determining phenotypes of the disease. Further studies are needed to make treatment of AMD more personalized and change our patient care.


 

Guarente Sirtuins, NAD and healthspan
Wednesday, Feb 18; 11:10am – 12:10pm
Room 1 - Main Hall

Chairperson: Kazuo Tsubota
Keio University School of Medicine, Japan
Speaker: Leonard Guarente, PhD
Glenn Laboratory for the Science of Aging, Massachusetts Institute of Technology 

SIR2 and related genes (sirtuins) are NAD-dependent deacetylases that link metabolism, protein acetylation and aging in a variety of species. Sirtuins are involved in the longevity conferred calorie restriction (CR). The mammalian sirtuins SIRT1-7 are involved in changes in stress resistance and metabolism that are triggered by CR, which not only extends life span, but also protects against many diseases of aging. In this talk, I will discuss new findings in the lab regarding SIRT1 and NAD+. I will also discuss the role of SIRT1 in adult stem cells. Our findings place sirtuins at the center of metabolism and health.

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Plenary Sessions

View the Plenary Session Abstracts   

1. AMD in Asians
Tuesday, Feb. 17; 9 – 11am
Room 1 - Mail Hall
Organizers: Tien Yin Wong, Singapore Eye Research Institute/ Duke-NUS Graduate Medical School, Singapore
Calvin CP Pang, The Chinese University of Hong Kong, Hong Kong

2. Genome-wide Association Study for Complex Eye Diseases 
Tuesday, Feb. 17; 9 – 11am
Room 2 - 501
Organizers: Nobuhisa Mizuki,Yokohama City University School of Medicine, Japan
Chiea Chuen Khor, Genome Institute of Singapore, Singapore"

3. Recent Advances in Retinal Basic Research 
Tuesday, Feb. 17; 9 – 11am
Room 3 - 502
Organizers: Shibo Tang, Central South University, China
Yuichiro Ogura,Nagoya City University, Japan

4. Normal Tension Glaucoma Update
Tuesday, Feb. 17; 9 – 11am
Room 4 - 503
Organizers: Kazuhisa Sugiyama, Kanazawa University Graduate School of Medical Science, Japan
Jost B. Jonas, Medical Faculty Mannheim, University Heidelberg, Germany
Goji Tomita, Toho University Ohashi Medical Center, Japan

5. Updates on Standardized Classifications/Severity Scales of Ocular Diseases: a Key for Successful Clinical Research 
Tuesday, Feb. 17;  9 – 11am
Room 5 - 315
Organizers: Mingguang Hem, Sun Yat-sen University, China
Shih-Jen Chen, Taipei Veterans General Hospital, Taiwan

6. Recent Trends in Regenerative Medicine
Wednesday, Feb. 18;  9 – 11am
Room 1 - Main Hall
Organizers: Kohji Nishida, Osaka University Graduate School of Medicine, Japan
Scheffer C. G. Tseng, R&D Department, TissueTech, Inc., USA

7. Cell Biology and Pathology of EMT
Wednesday, Feb. 18;  9 – 11am
Room 2 - 501
Organizers: John McAvoy, University of Sydney, Australia
Choun-Ki Joo, The Catholic University of Korea, South Korea
Tetsuro Oshika, Faculty of Medicine University of Tsukuba, Japan

8. Imaging in Uveitis
Wednesday, Feb. 18;  9 – 11am
Room 4 - 503
Organizers: Sunil Srivastava, Cleveland Clinic, USA
Annabelle A Okada, Kyorin University School of Medicine, Japan

9. Cutting Edge Aging Research
Thursday, Feb. 19; 9 – 11am
Room 1 - Main Hall
Organizers: Kazuo Tsubota, Keio University School of Medicine, Japan
Jonathan Crowston, University of Melbourne, Australia

10. New Insights into Corneal Cell Biology
Thursday, Feb. 19; 9 – 11am  
Room 2 - 501
Organizers: Shizuya Saika, Wakayama Medical University School of Medicine, Japan
Kyoung Yul Seo, Yonsei University College of Medicine, South Korea

11. Myopia; Genes or Enviroment?
Thursday, Feb 19; 9 – 11am  
Room 4 - 503
Organizers: David A. Mackey, University of Western Australia, Australia
Kyoko Ohno-Matsui, Tokyo Medical and Dental University, Japan

 


 
Symposia

View the Symposium Abstracts

1. New Strategies for Glaucoma Diagnosis and Treatment
2. Ocular Surface and Stromal Biology
3. Molecular Mechanisms in Diabetic Retinopathy
4. Science in Corneal and Refractive Surgery
5. Recent Topics of Neuro-Ophthalmology
6. What's New in IgG4 Related Ophthalmic Disease
7. Functional Testing of Vision
8. OCT, Clinical Use and Future
9. Friendship Makes it Possible! - Vision Van Project
10. Advances in Drug Delivery (In conjunction with ARVO)
11. The Contribution of the Retinal Circadian System to the Aging of the Retina
12. Update on Glaucoma Management (In conjunction with EVER)
13. Molecular Mechanisms in Age-related Macular Degeneration
14. Updates on Genetic Epidemiology in Ophthalmology: What's the Next Hope?
15. Metamorphopsia
16. Advances in Eye Research and NEI International Partnerships
17. Recent Advances in Dry Eye Research
18. Comparative Effectiveness Research in Ophthalmology
19. Cataract: Recent Advances in Etiopathogenic Signaling and Potential Therapies
20. Basic Research in Ocular Infection and Immunology
21. Retinal Imaging
22. Molecular Genetics of Eye Diseases
23. New Insight for Retinal Detachment, Damage and Treatment
24. Epigenetics in Ocular Development and Diseases
25.Inflammatory Mechanisms in Diabetic Retinopathy and Age-related Macular Degeneration
26. Recent topics in Anti-aging in Ophthalmology

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Special Interest Groups

View the Special Interest Group Abstracts

1. New Approaches to Infectious Keratitis
2. Primary Angle Closure Disease
3. Asian Eye Genetics Consortium (AEGC) and eyeGENE International
4. Mechanism of Retinal Degeneration
5. Corneal Endothelial Health and Disease
6. Retinal Development and Regeneration

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Host Organization

Department of Ophthalmology
Keio University School of Medicine
35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582 Japan


Congress Secretariat
The Asia-ARVO 2015 Secretariat will move to the conference venue on Feb. 15 

For inquiries, please contact:
2015asia-arvo@mediproduce.jp
Phone:  +81.45.228.6385
*number only valid from Feb. 15-19

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