Optic Nerve Degeneration and Ageing

Dec 05 - 07, 2012 Obergurgl, Austria


This conference explored the current state of our understanding of optic nerve degeneration, such as in glaucoma. It identified crucial problems and promising future research directions and initiated follow-up workshops for translational and biomarker research.

To stimulate ideas and discussion, leading experts from a variety of fields emphasized a cross-sectional, interdisciplinary approach. Speakers discussed the influence of ageing, oxidative stress, mitochondria, glia and autoimmunity in the pathogenesis of these processes, as well as their ability to protect the optic nerve against degeneration or to slow it down.

In addition to these basic mechanisms, speakers focused on understanding and identifying biomarkers in optic nerve degeneration. The emphasis was on ageing and its role in the disease pathogenesis and treatment approaches.

The conference brought together clinicians and basic scientists from different fields and highlighted translational research providing a platform for networking and stimulating discussions. Including:

  • What can we learn from the last decade and from other areas?
  • How can we accelerate progress in the application of results from basic science into diagnosis, follow-up, treatment and clinical trials in neurodegenerative diseases such as glaucoma?
  • How can promising scientific results translate successfully into clinical applications?

Target audience

Intended for basic scientists and clinicians to address important topics in translational research, including scientists in interdisciplinary areas such as neurology, neurodegenerations and autoimmunity.

Conference organizer

Franz H. Grus, MD, PhD
Head of Experimental Ophthalmology
Augenklinik der Universitätsmedizin der Johannes – Gutenberg Universität
Mainz, Germany

Jonathan G. Crowston, MBBS, PhD
Ringland Anderson Professor and Head of Ophthalmology, University of Melbourne
Director, Centre for Eye Research Australia
Melbourne, Australia


Phoenix research labs