Sunday, April 28, 1 - 2:30pm Lecture

The importance of animal research in the bench to bedside pipeline
Organizers: Neena Haider, Richard Libby and Darryl Overby
Speakers: Neena Haider, Douglas Gould, Monica Jablonski, Nick Di Girolamo and Cynthia Grosskreutz

Animal research has many roles in developing treatments for human disease. It is critical for basic science research aimed at identifying potential therapeutic targets. Also, new treatment paradigms utilizing novel technologies, including viral gene delivery, stem cell-mediated therapies, and nanoparticles all rely on animal models for development. Furthermore, animal models are used to determine the feasibility, safety and long-term stability of potential therapeutic interventions. It is important to note that animal models are crucial to unraveling and modeling findings from human patients. For instance, animal models have and will play a large role in understanding complex genomic studies and studies exploring the environmental influence in human disease. Thus, not only are animal models important for bringing treatments into the clinic they are also important in a reiterative process that is critical for understanding human disease and personalizing treatments. In this symposium, we discuss areas where animal research has driven and will drive the development of treatments and regenerative therapies for blinding diseases.

Win-win collaborations between academic and industry
Organizers: Derek Nankivil and Steven F. Abcouwer
Speakers: John Buch, Billy R. Hammond, Ashwath Jayagopal and Steven F. Abcouwer

In this time of excess pressure for accelerated growth, corporations are downsizing internal research capabilities and looking to external research contracts and academic partnerships. Thus, academic-Industry collaborations are an increasing source of basic science and technology development funding, fueling high impact innovations across the spectrum of sectors. This workshop will explore the potential impact that these win-win collaborations can provide for research and development programs.

China-ARVO Networking Forum
Organizers: David R. Hinton, Ke Yao and Shikun He
Speakers: W. Daniel Stamer, Jin Yuan,Gerard Sutton, Haidong Zou, Hossein Ameri and Hong Zhang

This is the 14th annual China – ARVO Networking Forum. The purpose of this event is to provide a platform for vision researchers from China, the USA and another country to interact, discuss and exchange knowledge in the field of vision research & ophthalmology and to promote collaboration among the scientists.

Speakers include leading ophthalmic researchers from China, the USA, and another country. At the upcoming meeting, topics will align with the 2019 ARVO “Bench to Bedside and Back” theme that will show the advanced researches in major blindness eye diseases. Everyone is welcome to attend the meeting; a limited lunch will be provided.

Grant writing: Early career funding opportunities
Organizers: Wenlin Zhang, Nawajes Mandal and Mehrnoosh Saghizadeh
Speakers: Neeraj Agarwal, John S. Penn, Matthew Helton and Elizabeth Zuniga Sanchez 

This workshop focuses on providing ARVO trainees with advice on strategies to prepare a successful early-career grant application. A panel of experts from government and non-governmental funding agencies and industry, as well as current K99/R00 awardee, will provide advice on application preparation and in career development.

Monday, April 29, 1:15 - 2:45pm

NIH-CSR peer review workshop Lecture
Organizers: Paek-Gyu Lee
Speakers: Michael Chaitin and Nataliya Gordiyenko

Sponsored by the NIH Center for Scientific Review (CSR), this workshop is designed to inform grant applicants, and reviewers about the NIH peer review process and provide information about the study sections that review visual system grant applications. Scientific Review Officers (SROs) from CSR will be on hand for the presentation and will be available to answer questions.

Member-In-Training career forum: Preparing for your future career NOW!
Organizers: Colleen McDowell, Esther Bowie, Joao Barbosa Breda and Barbara Wirostko
Speakers:Elizabeth Hartnett, Geeta Vemuganti, Abe Clark, Emily Chew, Stephen Rose and Barbara Wirostko

This workshop is aimed at helping students, post-docs, and fellows prepare for their next career move. Invited speakers will provide their perspectives on careers in academia (teaching and research), industry, NIH intramural laboratories, and nonprofit research foundations. Speakers will discuss lessons they have learned and what resources are available to make the transition. The small-group discussion will be held in the form of various roundtables focusing on topics ranging from preparing your CV, current activities and training you will need for various career choices, to negotiating a startup package.

Getting published: The light and dark sides…
Organizers: C. Gustavo de Moraes, Jason Porter and Pouya Alaghband
Speakers: Karla Zadnik,Steven J. Fliesler, Sarah Coupland and Michael D. Twa 

This workshop is part of an annual series co-sponsored by the ARVO Publications and Members-in Training Committees. As scholarly publishing continues to grow, so too do pressures on scientists to continue to write and publish excellent material while also allowing only the most completely reviewed and high quality of manuscripts to emerge from the peer-review process favorably. It is therefore essential that scientists not only develop the abilities to successfully communicate their research and evaluate manuscripts (as part of the peer-review process) but also be able to adapt to the changing landscape of publishing in effective and ethical manners. The goal of this workshop will be to discuss tips for successfully writing and reviewing manuscripts. Invited speakers will provide their perspectives on how to most effectively write your work for publication, how to avoid the sometimes “blurry” lines of plagiarism (including self-plagiarism), how to produce strong and ethical reviews, and how to understand the many different journal and author indices that currently exist, as well as why we should care about them.

VSS at ARVO – Vision after sight restoration
Organizer: Lynne Kiorpes, Ulrike Grunert and David Brainard
Speakers: Holly Bridge, Krystel Huxlin, Sharon Gilad-Gutnick and Geoff Boynton

Visual deprivation during development can have a profound effect on adult visual function, with congenital or early acquired blindness representing one extreme regarding the degree of deprivation and adult sight loss representing another. As better treatments for blindness become available, a critical question concerns the nature of vision after the restoration of sight and the level of remaining visual system plasticity. This symposium will highlight recent progress in this area, as well as how vision therapy can best be deployed to optimize the quality of post-restoration vision. This is the biennial VSS@ARVO symposium, features speakers from the Vision Sciences Society.

Tuesday, April 30, 7 - 8:30am 

Breakfast with the experts
Organizers: Members-in-Training Committee

Advance registration required. Trainees, students and junior faculty will benefit from this unique opportunity to network and gain valuable information from those who have been in your shoes! This very popular program offers informal discussions over breakfast on a wide range of topics to provide personal guidance, insight and skills to help you advance your career! Topics will focus on professional development, career guidance, and best practices of interest to basic and clinical trainees and clinician-scientists. A number of the roundtable topics will be specifically tailored to the needs of clinician-scientists.

Wednesday, May 1, 12:15 - 1:45pm

Overcoming the challenges of international collaboration in ocular research
Ester Carreño, M. Natalia Vergara and Kate Keller
Speakers: Gyan Prakash, Rupesh Agrawal, Carmen Ayuso, Richard Lee and Cristos Ifantides

The aim of the workshop is to share successful experiences of international collaborations, with special focus on overcoming the challenges of those collaborations, such as authorship in publications, data sharing, grant application and successful funding, legislation, collaboration agreement between countries and/or institutions, ethical or intellectual property issues, organizing teleconferences across different time zones, technology transfer, training manpower, etc.

Ethical challenges and solutions for CRISPR treatment in human eye disorders
Organizers: Yutao Liu, Pedram Hamrah and Muhammad Abdulrazik
Speakers: Budd Tucker, Stephen Tsang, Tara Moore and Peter Campochiaro

This workshop will focus on the ethical challenges and potential solutions for CRISPR treatments in human disorders, especially eye disease. The concept of gene editing is not novel, but CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated Protein 9) seems to be more advantageous than older technologies with higher precision and efficiency. Leading biotech and pharmacological companies in the field (such as Editas Medicine, Intellia Therapeutics, and CRISPR Therapeutics) are gearing up toward clinical trials in human subjects with a large investment of > $1 billion, indicating the high translational and clinical potential. As the CRISPR technique itself still evolves to become better, we still have to question ourselves whether we are ready to handle the safety and ethics of experimenting CRISPR intervention in human subjects. In this workshop, leading CRISPR scientists will share they're extensive clinical and research experience with the vision and ophthalmology community, with special reference to the safety and ethics of this novel method of gene editing in comparison to other technologies.

ARVO/WEAVR - Scientists as entrepreneurs (or How to apply your science to business)
Organizers: Stella Robertson, Terri L. Young and Kathryn S. Crawford
Speakers:  Adrienne Graves, Cynthia L. Grosskreutz, Cheryl Rowe-Rendleman, Barbara Wirostko and Kathryn S. Crawford

ARVO as an organization has created an ecosystem of shared knowledge, intellectual expertise, and physical infrastructure that supports entrepreneurship. Learning from entrepreneurs in the vision science field, the workshop panelists will share their stories of how they developed a career mindset to work in this space and find support for their projects. This workshop is designed to help those with ideas learn how to think strategically about the needs of the marketplace and a product’s value to a customer when developing their own technology.

Clinician-Scientist forum: How to become a successful clinician-scientist
Organizers: Eszter Szalai and Wenlin Zhang
Speakers:  Sophia X. Deng, Russell Van Gelder, Hans Grossniklaus, Neeraj Agarwal and Weizhong Lan 

Internationally renowned clinician-scientists at various stages in their careers will share their experiences and provide valuable advice on how to become a successful clinician-scientist. An NEI extramural representative will be available to discuss clinician-scientist specific funding mechanisms.

How to tell m (e) y (e) story? Why effective communication is needed now more than ever to increase research funding
Organizers: Peter Koulen, Teresa Puthussery and Pamela Martin
Speakers: Lauren Ayton, Gadi Wollstein, Stacy Pagos Haller, Maria B. Grant and Hosam Ibrahim-Elzembely 

Everyone loves a good story, but what makes a story great? Moreover, more importantly, what makes someone an effective storyteller? This interactive workshop, co-sponsored by ARVO’s AOC, MIT and GMC committees, will explore how to harness the power of storytelling to effectively communicate your research. We will feature successful leaders and rising stars in our field who will discuss how to shape your narrative to engage a variety of audiences including experts in your field, funding bodies, patient groups, and the general public. Our speakers will share real-life examples of how effective communication has helped them build strong and sustainable research programs, launch their careers and make a difference for the patients and communities they serve. Attendees will also learn about resources available to ARVO members including practical advice on dos and don'ts in communicating one’s research. Attendees will have the opportunity to work in small groups to implement strategies and practice the art of storytelling on their own research during the workshop. Attend this timely, practical and interactive workshop, which may even help you get that next grant!

Thursday, May 2, 12:15 - 1:45am Lecture

EVER/ARVO - The breadcrumb trail in glaucoma: From biology to the patient
Organizers: Alain BRON and Balwantray Chauhan
Speakers: Roberts Nickells, Adriana Di Paolo, Janey Wiggs, Balwantray Chauhan and Ted Garway-Heath

This workshop aims to appraise the current stage of knowledge in experimental and clinical glaucoma research. It will cover topics ranging from the fundamental pathophysiology of the disease through to clinical translation of future therapies.

Addressing global blindness through international research collaborations – next frontier for 2020
Organizers: Gyan Prakash
Speakers: Janey Wiggs, Pamela Sieving, Takeshi Iwata, Calvin Pang, Sudha Iyengar and S. Natarajan

As much as 90 percent of the global burden of eye disease is shouldered by developing countries, where many treatable diseases often go undiagnosed. About 39 million people around the world are blind, and a further 246 million are visually impaired, according to the WHO. Eighty percent of blindness is considered preventable; however, development of effective screening and treatment strategies require sustained research efforts that would benefit from international research collaborations. Several international research collaborative programs have been successful in bringing international colleagues to make significant contributions to vision research. However, wider participation of researchers is needed to advance high-quality science in many areas of vision research. A coordinated strategy for basic science and health services research will help in reducing the global burden of eye diseases and the implementation of research findings. This ARVO session will focus on several current and planned international research programs and will discuss the strategies and challenges in building international collaborations in vision research. The ARVO session will stimulate discussion on forming new research partnerships and address the current issues and challenges in international research collaborations.

Chinese Ophthalmological Society (COS) workshop
Organizers:  Ke YAO and Xiangtian ZHOU
Speakers: Ningli Wang, Xinghuai Sun, Maureen McCall, Paul Bernstein, Dongfeng Chen, Meidong Zhu and Xiangtian Zhou

This topic focuses on the pathological changes of various types of cells in common eye diseases and their role in the occurrence of eye diseases. It also introduces the research progress and clinical problems of stem cells in the treatment of common eye diseases. Special focus and introduction to the latest research progress of Chinese ophthalmology research experts. It provides a platform for understanding the latest developments and promoting exchanges and cooperation in China.

NEI grants workshop: New NIH regulations concerning human subject and animal research

Organizers: Michael A. Steinmetz and Grace L. Shen
Speakers: Maryabb Redford, Donald Everett, Cheri Wiggs, Brian Hoshaw, Grace Shen and Karen Smith 

Whether you are new to the NIH grant process, or established NEI investigators seeking information to successfully navigate your NEI grant applications and research protocols through human research protections review or Institutional Animal Care and Use Committee assurance, join this session to meet with the NEI Extramural Staff. During this session, you will learn about new regulations concerning Human Subject and Animal Models research and how it applies to extramural grants and how to ensure your institution is meeting the requirements or the policy and the law. There will be short presentations, Q&A, and roundtable discussion with the staff.