Sunday, April 29, 1 - 2:30pm

Pizza with the experts
Organizers: Members-in-Training Committee

Advance registration required. Trainees, students and junior faculty will benefit from this unique opportunity to network and gain valuable information from those who have been in your shoes! This very popular program offers informal discussions over a pizza lunch on a wide range of topics to provide personal guidance, insight and skills to help you advance your career! Topics will focus on professional development, career guidance, and best practices of interest to basic and clinical trainees and clinician-scientists. A number of the roundtable topics will be specifically tailored to the needs of clinician-scientists.

Experimental design for optimal animal research in the age of the 'reproducibility crisis.' (ARC)
Organizers: Jodhbir S. Mehta, Jack M. Sullivan, and Neena Haider
Speakers: Abbot Clark, Catherine Bowes Rickman, Mae Gordon, Marie Ortega and Paul Kaufmann

Animal models play a vital role in ocular research. Data obtained using animal models provide vital pre-clinical evidence for the decision of whether to continue to clinical trials or not. In vivo experiments also are fundamental for determining the molecular basis of physiology and pathophysiology, especially in complex tissues like the eye. The importance of appropriate design and execution of animal experiments cannot be overstated. The Proper experimental design is necessary for obtaining valid, interpretable results. To properly use animals, it is important that an appropriate animal model is chosen, proper outcome measures and time points are selected, the experiment is properly powered for all outcome measures, and the experiment is appropriately designed to minimize bias. It is also important that the experimental design takes into account animal welfare and the goal of the three Rs, reduce, replace and refinement of methods that alleviate or minimize potential pain, suffering or distress and enhance animal welfare for the animals used. The Animals in Research Committee Workshop for ARVO 2018 will focus the importance of developing the appropriate experimental design for animal research. Organized by the ARVO Animals in Research Committee.

Grant writing: How to get your proposals funded (MIT)
Organizers: Richard Blanch, Wenlin Zhang and Michael Elliott
Speakers: Neeraj Agarwal, Nicholas Delamere, Diane Bovenkamp and Matthew Helton

This workshop focuses on providing ARVO trainees with advice on strategies to prepare a successful grant application. A panel of experts from government and non-governmental funding agencies and industry, including grant review panel members and foundation and industry sources will provide advice on application preparation, what separates fundable from unfundable applications, and strategies to engage industry support.

Monday, April 30, 1:30 3pm

NIH-CSR: Information and Expectations for the Peer Review of Grant Applications
Organizers: Michael H. Chaitin
Speakers: Nataliya Gordiyenko, Paek-Gyu Lee and Maqsood A. Wani

Sponsored by the Center for Scientific Review (CSR) at the National Institutes of Health (NIH) this workshop is designed to inform grant applicants about the NIH peer review process and also explain what reviewers look for in applications, as well as provide information about the study sections that review visual system grant applications. Scientific Review Officers (SROs) from CSR will be present for the presentation and to answer any questions.

China-ARVO Networking Forum
Organizers: David R. Hilton, Shikun He, and Ke Yao
Speakers: Juan Ye, Mark Humayun, Zhengqin Yin, Ningli Wang, Zongming Sun, Michel Cayouette, Sarah X. Zhang, and D. Hua Yan

This is the 13th annual China – ARVO Networking Forum. The purpose of this event is to provide a platform for vision researchers from China, the USA and another country to interact, discuss and exchange knowledge in the field of vision research & ophthalmology and to promote collaboration among the scientists. Speakers include leading ophthalmic researchers from China, the USA, and another country. At the upcoming meeting, topics will align with the 2018 ARVO "Stand Strong for Science: Stand for Strong Vision Science" theme that will show the advanced researchers in major blindness eye diseases. Everyone is welcome to attend the meeting; a limited lunch will be provided

Civic and community engagement for stronger science: Effective communication strategies (DIC)
Organizers: Dolly Padovani-Claudio, Jerome Wujek, Natalia Vergara, and Lin Cheng
Speakers: Maria Zacharias, Peter Soliz, Leonard Seibold and Matthew Windsor

As scientists, we strive to understand and become experts in our fields to make an impact in our diverse world. Effective communication beyond disciplines is necessary to build a scientific case for what we do and to engage diverse groups in order to share our findings, gain funding, translate our work to patient care, and promote unwavering support for our efforts to make an impact. Science communication is more effective when our focus goes beyond content to structure so that the message is understood. This workshop will allow you to make a difference, by learning how to communicate with diverse audiences including lay-people, experts in other fields, patients, technology developers, policy makers, and the general public about what you know, what you do, and why vision science matters. Our speakers include Maria Zacharias (Director of the NEI Communications Office), Dr. Peter Soliz (Chief Executive Officer of VisionQuest Biomedical, Inc.) and Dr. Matthew Windsor (ARVO Senior Manager of Science Communications). Based on their experiences working with non-scientists, at-risk patient populations, and policy makers, they will share principles of scientific communication and outreach important for all of us to communicate technical information to a diverse variety of audiences including under-represented populations. We hope that at the end of this workshop you will feel motivated to enter into a meaningful dialogue with interested audiences about why what we do matters and how it impacts the world so that together we can take action for stronger science. We believe this proposed workshop will serve the goals of promoting communication of the value of vision science and of engaging under-represented and diverse communities to be involved in research and the products of its translation to health services.

Multi-omics, mechanisms and stratification – paradigms for understanding and targeting immune responses in disease
Organizers: Andrew Dick (EVER/ARVO)
Speakers: Lai Wei, Jonas Kuiper, Richard Lee and Jim Rosenbaum

The use of multiple genomic/transcriptomic platforms alongside the platforms that permit in-depth endophenotyping for immune responses in man has opened unparalleled advantages to understand immune responses, disease, and therapeutic stratification. This will enable a refined molecular classification of disease alongside targets and prediction of responses to therapies. We can learn from rare inflammatory disorders, and we can translate findings across disease groups both organ-specific and systemic. The workshop will focus on key advances that will take us away from traditional classifications to a more targeted and personalized approach to disease and therapies.

Keys to writing manuscripts and determining where to publish (PUBS & MIT)
Organizers: Vishal Jhanji, Pouya Alaghband, and Jason Porter
Speakers: Elizabeth G. Phimister, Joseph Carroll, Martine Jager and Andrew Watson

This workshop is part of an annual series co-sponsored by the ARVO Publications and Members-in-Training Committees. Peer-reviewed publications are not only a valuable tool to share one's research findings but are also more commonly being included in metrics used to assess one's research performance and productivity. The ability to effectively communicate one's research in the peer-reviewed literature has, therefore, become an increasingly important skill to master and implement. The goal of this workshop will be to discuss nuances of the writing and journal selection (or avoidance) processes. Invited speakers will provide their perspectives on how to most effectively write your work for publication, how to confront the challenging issues of authorship and factors to consider regarding their listing, how to recognize and negotiate predatory journals and how to understand preprint publications and their potential impact on the peer-reviewed literature.

Tuesday, May 1, 1:30 3pm

Bridging and bootstrapping in today's risk averse environment (CRC)
Organizers: Cagri G. Besirli and Steven F. Abcouwer
Speakers: Gregory Jackson, Thomas Chalberg, David Zacks, Tushar Ranchod, and Joseph Izatt

The Ophthalmology drug and device market are growing at a rapid pace fueled by a constant stream of novel therapeutics and devices entering the field. Securing early funding is one of the most critical steps for translating innovations into commercially viable products. This workshop will feature leading ophthalmic entrepreneurs with broad experience in academics, private practice, and industry. Drawing from their diverse backgrounds and experiences, these speakers will discuss bootstrapping to bridge the funding gap that must be overcome in order to get an idea off the ground and into a clinical trial.

Clinician-Scientist Forum: How to become a successful clinician-scientist (MIT)
Organizers: Jennifer Chao and Eszter Szalai
Speakers: Paul A. Sieving, Kathryn Pepple, Ula Jurkunas, Hans Grossniklaus, Russell Van Gender and Neeraj Agarwal

Internationally renowned clinician-scientists at various stages in their careers will share their experiences and provide valuable advice on how to become a successful clinician-scientist. An NEI extramural representative will be available to discuss clinician-scientist specific funding mechanisms.

How to promote vision research to patients and policymakers in different regions of the world (AOC & GMCs)
Organizers: Juliet Moncaster and Daniel Rathbun
Speakers: James Jorkasky, Jose Sahel Jr., Masayo Takahashi, Dorairajan Balasubramanian and Avril Daly

Communicating the importance of our vision research to society is important. How should we work with patients, patient advocacy group, policy/law makers and funding agencies to effectively promote the importance of vision research and funding?
During this workshop, we will explore how science advocacy works, including engagement of patients and patient advocacy groups and how this may differ depending on the region in the world.

Addressing Global Blindness and Eye Diseases through International Research
Organizers: Gyan "John" Prakash
Speakers: Rachel Bishop, Gyan "John" Prakash, Pawan Sinha, Ronnie George, Rubens Belfort, Jr., Janey Wiggs and Umang Mathur

As much as 90 percent of the global burden of eye disease is shouldered by developing countries, where many treatable diseases often go undiagnosed. About 39 million people around the world are blind and a further 246 million are not able to see properly, according to the WHO. Eighty percent of blindness is considered preventable, however a comprehensive research strategy and international research collaborations between the developed and developing world need to increase. A few collaborative programs have been successful in bringing international colleagues to make significant contributions to vision research. However, a wider participation of researchers is needed to advance the high-quality science in many areas of vision research. A coordinated strategy for basic science and health services research will help in reducing the global burden of eye diseases and implementation of research findings. The ARVO session will focus on a few successful international research collaborative studies and discuss the strategies and challenges in building international collaborations for the NIH programs. The ARVO session will stimulate discussion on forming new research partnerships and address the current issues and challenges in international research collaborations.

Wednesday, May 2, 6:45 - 8:15am     

Breakfast with the experts
Organizers: Members-in-Training Committee

Advance registration required. Trainees, students and junior faculty will benefit from this unique opportunity to network and gain valuable information from those who have been in your shoes! This very popular program offers informal discussions over breakfast on a wide range of topics to provide personal guidance, insight and skills to help you advance your career! Topics will focus on professional development, career guidance, and best practices of interest to basic and clinical trainees and clinician-scientists. A number of the roundtable topics will be specifically tailored to the needs of clinician-scientists.

Wednesday, May 2, 1:30 - 3pm

Understanding the NEI Granting Process
Organizers: Michael A. Steinmetz and Grace L. Shen
Speakers: George McKie, Ellen Lieberman, Houmam Araj, Paul Sheehy and Grace L. Shen

Whether you are new to the NIH grant process, or an established NEI investigator seeking to hear about how new programs and policies may impact you and your institutions, join this session to meet with the Director and staff of the NEI Division of Extramural Science Programs. During this session, you will learn about new opportunities and current policy issues, key compliance requirements governing NIH awards, and how to get your great research idea to NEI for funding consideration. There will be short presentations and ample time for Q&As on the NEI granting process.

Making ARVO more accessible: Experience from countries with emerging vision-oriented research agenda (GMC)
Organizers: Daniel Rathbun, Muhammad Abdulrazik, Thanasis Panorgias and Shyam Chaurasia
Speakers: Daniel Rathbun, Ningli Wang, Dorairajan Balasubramanian, Solange Salomão and Oksana Vitovska 

The workshop will provide highlights on the Infrastructure for vision and ophthalmology related research in China, India, Brazil and Eastern Europe countries. These are populous countries with well recognized academic systems, and emerging vision-oriented research agendas that nevertheless maintain low accessibility to ARVO activities. Speakers will review local prominent research projects in the field, unique research infrastructure and research database initiatives in their countries that could be valuable for potential global research partners. Discussions will address obstacles that contribute to the relatively low global visibility of vision and ophthalmology research from emerging research countries and the low accessibility to ARVO activities.

The path from bench to bedside: Professional development and entrepreneurship (MIT)
Organizers: Rafal Farjo, Barbara Wirostko and João Barbosa-Breda
Speakers: Barbara Wirostko, Rafal Farjo, Gary Novack and Patrick Healy

The objective of this workshop is to discuss the stepwise manner in which new therapeutics are advanced from initial discovery through clinical evaluation regulatory agencies. The entire therapeutic development process will be summarized and laid out in a stepwise manner. Attendees will walk away with knowledge on:
1. Obtaining funding to advance novel therapeutic concepts
2. How to demonstrate adequate proof-of-concept for a specific clinical indication
3. Regulatory hurdles necessary to advance a new therapeutic into clinical trial
4. Phases of clinical trials and the effect of the desired indication on timeline

Data sharing: Clinical science in the era of artificial intelligence (ERHR)
Organizers: Daniela Ferrara, Larry Kagemann, Muhammad Abdulrazik and Pedram Hamrah
Speakers: Nadia Waheed, Andrew Beam, Douglas Foster, Charles Reisman, Malvina Eydelman and Jeffrey Willis

Data Sharing is recognized as a key driver of open scientific inquiry and a conduit to stimulating new investigations and analysis. International initiatives in Data Sharing are growing consistently, as much as the magnitude of data repositories. Of particular interest to this workshop is Data sharing in ophthalmology and visual sciences, which can bring innovative strategies to clinical research, identify new biomarkers and study endpoints, and accelerate scientific advances, with positive impact across scientific fields – from experimental basic science to patient care. However, ethics and regulations of Data Sharing must protect data integrity and must assure that private or potentially sensitive patient's information is not revealed. Under the right circumstances and for the right reasons, Data Sharing between organizations can play a crucial role in serving science. For such, fit-for-purpose governance frameworks should support responsible sharing of information. In this workshop, experts from academia, industry and regulatory authorities will engage in a timely discussion about opportunities, challenges and best practices related to Data Sharing.